Mouse Msl3 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Msl3
Locus ID	17692
Kit Components	GA202724G1, Msl3 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA202724G2, Msl3 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA202724G3, Msl3 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Disclaimer	These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Reference Data
RefSeq	NM_010832, NM_001370791, NM_001370792, NM_001370793, NM_001370794, NM_001370795, NM_001370796, NM_001370797, NM_001370798, NM_001370799
Synonyms	AU018931; Msl3l1; Msl31
Summary	Has a role in chromatin remodeling and transcriptional regulation. Has a role in X inactivation. Component of the MSL complex which is responsible for the majority of histone H4 acetylation at 'Lys-16' which is implicated in the formation of higher-order chromatin structure. Specifically recognizes histone H4 monomethylated at 'Lys-20' (H4K20Me1) in a DNA-dependent manner and is proposed to be involved in chromosomal targeting of the MSL complex.[UniProtKB/Swiss-Prot Function]

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