Mouse Mef2a activation kit by CRISPRa

CAT#: GA202628

Mef2a CRISPRa kit - CRISPR gene activation of mouse myocyte enhancer factor 2A



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CNY 12,255.00


货期*
4周

规格
    • 1 kit

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经常一起买 (1)
MEF2A Antibody - N-terminal region
    • 50 ug

CNY 4,381.00

Specifications

Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol Mef2a
Locus ID 17258
Kit Components

GA202628G1, Mef2a gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA202628G2, Mef2a gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA202628G3, Mef2a gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077

Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Reference Data
RefSeq NM_001033713, NM_001291191, NM_001291192, NM_001291195, NM_001291196, NM_001357324, NM_001357325
Synonyms A430079H05Rik
Summary Transcriptional activator which binds specifically to the MEF2 element, 5'-YTA[AT](4)TAR-3', found in numerous muscle-specific genes. Also involved in the activation of numerous growth factor- and stress-induced genes. Mediates cellular functions not only in skeletal and cardiac muscle development, but also in neuronal differentiation and survival. Plays diverse roles in the control of cell growth, survival and apoptosis via p38 MAPK signaling in muscle-specific and/or growth factor-related transcription. In cerebellar granule neurons, phosphorylated and sumoylated MEF2A represses transcription of NUR77 promoting synaptic differentiation. Associates with chromatin to the ZNF16 promoter (By similarity).[UniProtKB/Swiss-Prot Function]
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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