Mouse Matk activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Matk
Locus ID	17179
Kit Components	GA202581G1, Matk gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA202581G2, Matk gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA202581G3, Matk gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Disclaimer	These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Reference Data
RefSeq	NM_001285853, NM_001285854, NM_001285855, NM_010768
Synonyms	CHK; HYL; Ntk; p56ntk
Summary	Could play a significant role in the signal transduction of hematopoietic cells. May regulate tyrosine kinase activity of SRC-family members in brain by specifically phosphorylating their C-terminal regulatory tyrosine residue which acts as a negative regulatory site. It may play an inhibitory role in the control of T-cell proliferation.[UniProtKB/Swiss-Prot Function]

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