Mouse Ccndbp1 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Ccndbp1
Locus ID	17151
Kit Components	GA202561G1, Ccndbp1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA202561G2, Ccndbp1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA202561G3, Ccndbp1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Disclaimer	These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Reference Data
RefSeq	NM_010761, NM_001355127
Synonyms	AU022347; DIP1; GCIP; Maid; SECC-8; SSEC-8
Summary	May negatively regulate cell cycle progression. May act at least in part via inhibition of the cyclin-D1/CDK4 complex, thereby preventing phosphorylation of RB1 and blocking E2F-dependent transcription (By similarity). May be required for hepatocyte proliferation.[UniProtKB/Swiss-Prot Function]

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