Mouse Mxd3 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Mxd3
Locus ID	17121
Kit Components	GA202542G1, Mxd3 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA202542G2, Mxd3 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA202542G3, Mxd3 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Disclaimer	These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Reference Data
RefSeq	NM_016662
Synonyms	4631412E13Rik; bHLHc13; Mad3
Summary	Transcriptional repressor. Binds with MAX to form a sequence-specific DNA-binding protein complex which recognizes the core sequence 5'-CAC[GA]TG-3'. Antagonizes MYC transcriptional activity by competing for MAX and suppresses MYC dependent cell transformation.[UniProtKB/Swiss-Prot Function]

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