Mouse Itgax activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Itgax
Locus ID	16411
Kit Components	GA202202G1, Itgax gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA202202G2, Itgax gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA202202G3, Itgax gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Disclaimer	These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Reference Data
RefSeq	NM_021334, NM_001363984, NM_001363985
Synonyms	AI449405; Cd11c; Cr4; N418
Summary	Integrin alpha-X/beta-2 is a receptor for fibrinogen. It recognizes the sequence G-P-R in fibrinogen. It mediates cell-cell interaction during inflammatory responses. It is especially important in monocyte adhesion and chemotaxis (By similarity).[UniProtKB/Swiss-Prot Function]

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