Mouse Il12rb2 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Il12rb2
Locus ID	16162
Kit Components	GA202121G1, Il12rb2 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA202121G2, Il12rb2 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA202121G3, Il12rb2 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Disclaimer	These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Reference Data
RefSeq	NM_001311141, NM_008354
Synonyms	A930027I18Rik; Ifnm; IL-12RB2
Summary	Receptor for interleukin-12. This subunit is the signaling component coupling to the JAK2/STAT4 pathway. Promotes the proliferation of T-cells as well as NK cells. Induces the promotion of T-cells towards the Th1 phenotype by strongly enhancing IFN-gamma production. Can also activate STAT3.[UniProtKB/Swiss-Prot Function]

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