Mouse Il11ra1 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Il11ra1
Locus ID	16157
Kit Components	GA202116G1, Il11ra1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA202116G2, Il11ra1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA202116G3, Il11ra1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Disclaimer	These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Reference Data
RefSeq	NM_001163401, NM_001172054, NM_010549
Synonyms	AI314697; GP130; Il-11ra; Il11ra; Il11ra2; NR1
Summary	Receptor for interleukin-11. The receptor systems for IL6, LIF, OSM, CNTF, IL11 and CT1 can utilize IL6ST for initiating signal transmission. The IL11/IL11RA/IL6ST complex may be involved in the control of proliferation and/or differentiation of skeletogenic progenitor or other mesenchymal cells. Essential for the normal development of craniofacial bones and teeth.[UniProtKB/Swiss-Prot Function]

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