Mouse Ifngr1 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Ifngr1
Locus ID	15979
Kit Components	GA202082G1, Ifngr1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA202082G2, Ifngr1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA202082G3, Ifngr1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Disclaimer	These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Reference Data
RefSeq	NM_010511
Synonyms	CD119; Ifgr; IFN-gammaR; Ifngr; Nktar
Summary	Associates with IFNGR2 to form a receptor for the cytokine interferon gamma (IFNG) (PubMed:2530582, PubMed:2532365, PubMed:2137461, PubMed:2531896, PubMed:2530216). Ligand binding stimulates activation of the JAK/STAT signaling pathway (By similarity).[UniProtKB/Swiss-Prot Function]

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