Mouse Hsd11b2 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Hsd11b2
Locus ID	15484
Kit Components	GA201998G1, Hsd11b2 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA201998G2, Hsd11b2 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA201998G3, Hsd11b2 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Disclaimer	These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Reference Data
RefSeq	NM_008289
Synonyms	11HSD2
Summary	Catalyzes the conversion of cortisol to the inactive metabolite cortisone. Modulates intracellular glucocorticoid levels, thus protecting the nonselective mineralocorticoid receptor from occupation by glucocorticoids.[UniProtKB/Swiss-Prot Function]

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