Mouse Hira activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Hira
Locus ID	15260
Kit Components	GA201904G1, Hira gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA201904G2, Hira gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA201904G3, Hira gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Disclaimer	These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Reference Data
RefSeq	NM_010435, NM_001005228
Synonyms	AA138857; D16Ertd95e; Gm15797; N28177; OTTMUSG00000026264; Tuple1
Summary	Required for the periodic repression of histone gene transcription during the cell cycle (By similarity). Cooperates with ASF1A to promote replication-independent chromatin assembly. Required for the formation of senescence-associated heterochromatin foci (SAHF) and efficient senescence-associated cell cycle exit.[UniProtKB/Swiss-Prot Function]

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