Mouse Lilrb4a activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Lilrb4a
Locus ID	14728
Kit Components	GA201686G1, Lilrb4a gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA201686G2, Lilrb4a gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA201686G3, Lilrb4a gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Disclaimer	These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Reference Data
RefSeq	NM_001291894, NM_013532
Synonyms	CD85K; gp49; Gp49b; HM18; ILT3; Lilrb4; LIR-5
Summary	Receptor for class I MHC antigens. Involved in the down-regulation of the immune response and the development of tolerance. Interferes with TNFRSF5-signaling and NF-kappa-B up-regulation. Inhibits receptor-mediated phosphorylation of cellular proteins and mobilization of intracellular calcium ions (By similarity).[UniProtKB/Swiss-Prot Function]

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