Mouse Got2 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Got2
Locus ID	14719
Kit Components	GA201680G1, Got2 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA201680G2, Got2 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA201680G3, Got2 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Disclaimer	These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Reference Data
RefSeq	NM_010325
Synonyms	AL022787; FABP-pm; Got-2; Kyat4; mAspAT
Summary	Catalyzes the irreversible transamination of the L-tryptophan metabolite L-kynurenine to form kynurenic acid (KA). Plays a key role in amino acid metabolism. Important for metabolite exchange between mitochondria and cytosol. Facilitates cellular uptake of long-chain free fatty acids.[UniProtKB/Swiss-Prot Function]

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