Mouse Fkbp8 activation kit by CRISPRa

CAT#: GA201433

Fkbp8 CRISPRa kit - CRISPR gene activation of mouse FK506 binding protein 8



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CNY 12,255.00


货期*
4周

规格
    • 1 kit

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Specifications

Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol Fkbp8
Locus ID 14232
Kit Components

GA201433G1, Fkbp8 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA201433G2, Fkbp8 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA201433G3, Fkbp8 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077

Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Reference Data
RefSeq NM_001111066, NM_001199631, NM_010223
Synonyms 38kDa; FKBP-8; FKBP-38; Fkbp38
Summary Constitutively inactive PPiase, which becomes active when bound to calmodulin and calcium. Seems to act as a chaperone for BCL2, targets it to the mitochondria and modulates its phosphorylation state. The BCL2/FKBP8/calmodulin/calcium complex probably interferes with the binding of BCL2 to its targets. The active form of FKBP8 may therefore play a role in the regulation of apoptosis (By similarity). Required for normal embryonic development.[UniProtKB/Swiss-Prot Function]
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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