Mouse Dyrk1b activation kit by CRISPRa

CAT#: GA201157

Dyrk1b CRISPRa kit - CRISPR gene activation of mouse dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1b



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CNY 12,255.00


货期*
4周

规格
    • 1 kit

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Specifications

Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol Dyrk1b
Locus ID 13549
Kit Components

GA201157G1, Dyrk1b gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA201157G2, Dyrk1b gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA201157G3, Dyrk1b gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077

Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Reference Data
RefSeq NM_001037957, NM_001271370, NM_010092
Synonyms Mirk
Summary Dual-specificity kinase which possesses both serine/threonine and tyrosine kinase activity. Enhances the transcriptional activity of TCF1/HNF1A and FOXO1. Inhibits epithelial cell migration. Mediates colon carcinoma cell survival in mitogen-poor environments. Inhibits the SHH and WNT1 pathways, thereby enhancing adipogenesis. In addition, promotes expression of the gluconeogenic enzyme glucose-6-phosphatase (G6PC).[UniProtKB/Swiss-Prot Function]
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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