Mouse Cbx5 activation kit by CRISPRa
CAT#: GA200572
Cbx5 CRISPRa kit - CRISPR gene activation of mouse chromobox 5
CNY 12,255.00
Specifications
Product Data | |
Format | 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug) |
Symbol | Cbx5 |
Locus ID | 12419 |
Kit Components | GA200572G1, Cbx5 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA200572G2, Cbx5 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA200572G3, Cbx5 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077 |
Disclaimer | These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc. |
Reference Data | |
RefSeq | NM_001076789, NM_001110216, NM_007626, NM_001358950 |
Synonyms | 2610029O15Rik; C75991; HP1; Hp1a; Hp1alpha |
Summary | Component of heterochromatin that recognizes and binds histone H3 tails methylated at 'Lys-9' (H3K9me), leading to epigenetic repression. In contrast, it is excluded from chromatin when 'Tyr-41' of histone H3 is phosphorylated (H3Y41ph). Can interact with lamin-B receptor (LBR). This interaction can contribute to the association of the heterochromatin with the inner nuclear membrane. Involved in the formation of functional kinetochore through interaction with MIS12 complex proteins (By similarity).[UniProtKB/Swiss-Prot Function] |
Documents
Resources
基因表达相关资源 |
Other Versions
SKU | Description | Size | Price |
---|---|---|---|
KN502613 | Cbx5 - KN2.0, Mouse gene knockout kit via CRISPR, non-homology mediated. |
CNY 8,680.00 |