Mouse Cacnb3 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Cacnb3
Locus ID	12297
Kit Components	GA200485G1, Cacnb3 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA200485G2, Cacnb3 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA200485G3, Cacnb3 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Disclaimer	These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Reference Data
RefSeq	NM_001044741, NM_001286226, NM_007581, NM_001356543
Synonyms	Beta3; Ca(v)beta3; CAB3; Cchb3
Summary	Regulatory subunit of the voltage-gated calcium channel that gives rise to L-type calcium currents (PubMed:24751537). Increases CACNA1B peak calcium current and shifts the voltage dependencies of channel activation and inactivation (By similarity). Increases CACNA1C peak calcium current and shifts the voltage dependencies of channel activation and inactivation (By similarity).[UniProtKB/Swiss-Prot Function]

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