Mouse Cacnb2 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Cacnb2
Locus ID	12296
Kit Components	GA200484G1, Cacnb2 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA200484G2, Cacnb2 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA200484G3, Cacnb2 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Disclaimer	These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Reference Data
RefSeq	NM_001252533, NM_001309519, NM_023116, NR_045533
Synonyms	AW060387; CAB2; Cavbeta2; Cchb2
Summary	The beta subunit of voltage-dependent calcium channels contributes to the function of the calcium channel by increasing peak calcium current, shifting the voltage dependencies of activation and inactivation, modulating G protein inhibition and controlling the alpha-1 subunit membrane targeting.[UniProtKB/Swiss-Prot Function]

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