Mouse Serpinc1 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Serpinc1
Locus ID	11905
Kit Components	GA200301G1, Serpinc1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA200301G2, Serpinc1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA200301G3, Serpinc1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Disclaimer	These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Reference Data
RefSeq	NM_080844
Synonyms	AI114908; At-3; At3; ATIII
Summary	Most important serine protease inhibitor in plasma that regulates the blood coagulation cascade. AT-III inhibits thrombin, matriptase-3/TMPRSS7, as well as factors IXa, Xa and XIa. Its inhibitory activity is greatly enhanced in the presence of heparin (By similarity).[UniProtKB/Swiss-Prot Function]

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