Mouse Chrnb2 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Chrnb2
Locus ID	11444
Kit Components	GA200036G1, Chrnb2 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA200036G2, Chrnb2 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA200036G3, Chrnb2 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Disclaimer	These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Reference Data
RefSeq	NM_009602
Synonyms	Acrb-2; Acrb2; C030030P04Rik; [b]2-nAchR
Summary	After binding acetylcholine, the AChR responds by an extensive change in conformation that affects all subunits and leads to opening of an ion-conducting channel across the plasma membrane permeable to sodiun ions.[UniProtKB/Swiss-Prot Function]

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