Human C1orf187 (DRAXIN) activation kit by CRISPRa
CAT#: GA117795
DRAXIN CRISPRa kit - CRISPR gene activation of human dorsal inhibitory axon guidance protein
CNY 12,255.00
Specifications
Product Data | |
Format | 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug) |
Symbol | DRAXIN |
Locus ID | 374946 |
Kit Components | GA117795G1, C1orf187 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA117795G2, C1orf187 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA117795G3, C1orf187 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077 |
Disclaimer | These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc. |
Reference Data | |
RefSeq | NM_198545 |
Synonyms | AGPA3119; C1orf187; neucrin; UNQ3119 |
Summary | Chemorepulsive axon guidance protein required for the development of spinal cord and forebrain commissures. Acts as a chemorepulsive guidance protein for commissural axons during development. Able to inhibit or repel neurite outgrowth from dorsal spinal cord. Inhibits the stabilization of cytosolic beta-catenin (CTNNB1) via its interaction with LRP6, thereby acting as an antagonist of Wnt signaling pathway.[UniProtKB/Swiss-Prot Function] |
Documents
Resources
基因表达相关资源 |
Other Versions
SKU | Description | Size | Price |
---|---|---|---|
KN410701 | DRAXIN - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. |
CNY 8,680.00 |