Human AMIGO2 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	AMIGO2
Locus ID	347902
Kit Components	GA117669G1, AMIGO2 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA117669G2, AMIGO2 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA117669G3, AMIGO2 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Disclaimer	These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Reference Data
RefSeq	NM_001143668, NM_181847, NM_001370299
Synonyms	ALI1; AMIGO-2; DEGA
Summary	Required for depolarization-dependent survival of cultured cerebellar granule neurons. May mediate homophilic as well as heterophilic cell-cell interaction with AMIGO1 or AMIGO3. May contribute to signal transduction through its intracellular domain. May be required for tumorigenesis of a subset of gastric adenocarcinomas.[UniProtKB/Swiss-Prot Function]

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