Human CLEC4G activation kit by CRISPRa
CAT#: GA117420
CLEC4G CRISPRa kit - CRISPR gene activation of human C-type lectin domain family 4 member G
CNY 12,255.00
CNY 8,170.00
Specifications
Product Data | |
Format | 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug) |
Symbol | CLEC4G |
Locus ID | 339390 |
Kit Components | GA117420G1, CLEC4G gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA117420G2, CLEC4G gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA117420G3, CLEC4G gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077 |
Disclaimer | These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc. |
Reference Data | |
RefSeq | NM_001244856, NM_198492 |
Synonyms | DTTR431; LP2698; LSECtin; UNQ431 |
Summary | This gene encodes a glycan-binding receptor and member of the C-type lectin family which plays a role in the immune response. C-type lectin receptors are pattern recognition receptors located on immune cells that play a role in the recognition and uptake of both self and non-self glycoproteins as well as mediating cell adhesion, glycoprotein clearance, and cell signaling functions. This gene's protein binds complex-type N-glycans of the viral envelope proteins of Ebola virus, West Nile filovirus, and SARS coronavirus, but not HIV or hepatitis C virus. In mouse, this protein has been shown to recognize activated T-cells and to negatively regulate T-cell receptor-mediated signalling. It also acts as a novel, liver-specific regulator of NK cell-mediated immunity in mouse. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Apr 2020] |
Documents
Resources
基因表达相关资源 |
Other Versions
SKU | Description | Size | Price |
---|---|---|---|
KN410798 | CLEC4G - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. |
CNY 8,680.00 |