Human Eph receptor A6 (EPHA6) activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	EPHA6
Locus ID	285220
Kit Components	GA117202G1, Eph receptor A6 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA117202G2, Eph receptor A6 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA117202G3, Eph receptor A6 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Disclaimer	These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Reference Data
RefSeq	NM_001080448, NM_001278300, NM_001278301, NM_173655
Synonyms	EHK-2; EHK2; EK12; EPA6; HEK12; PRO57066
Summary	Receptor tyrosine kinase which binds promiscuously GPI-anchored ephrin-A family ligands residing on adjacent cells, leading to contact-dependent bidirectional signaling into neighboring cells. The signaling pathway downstream of the receptor is referred to as forward signaling while the signaling pathway downstream of the ephrin ligand is referred to as reverse signaling (By similarity).[UniProtKB/Swiss-Prot Function]

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