Human ASC2 (PYDC1) activation kit by CRISPRa
CAT#: GA116933
PYDC1 CRISPRa kit - CRISPR gene activation of human pyrin domain containing 1
CNY 12,255.00
CNY 1,999.00
CNY 2,700.00
CNY 1,200.00
CNY 3,705.00
CNY 800.00
Specifications
Product Data | |
Format | 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug) |
Symbol | PYDC1 |
Locus ID | 260434 |
Kit Components | GA116933G1, ASC2 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA116933G2, ASC2 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA116933G3, ASC2 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077 |
Disclaimer | These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc. |
Reference Data | |
RefSeq | NM_152901 |
Synonyms | ASC2; cPOP1; POP1; PYC1 |
Summary | Associates with PYCARD/ASC and modulates its ability to collaborate with MEFV/pyrin and NLRP3/cryopyrin in NF-kappa-B and pro-caspase-1 activation. Suppresses kinase activity of NF-kappa-B inhibitor kinase (IKK) complex, expression of NF-kappa-B inducible genes and inhibits NF-kappa-B activation by cytokines and LPS.[UniProtKB/Swiss-Prot Function] |
Documents
Resources
基因表达相关资源 |
Other Versions
SKU | Description | Size | Price |
---|---|---|---|
KN411240 | PYDC1 - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. |
CNY 8,680.00 |