Human GPR97 (ADGRG3) activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	ADGRG3
Locus ID	222487
Kit Components	GA116669G1, GPR97 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA116669G2, GPR97 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA116669G3, GPR97 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Disclaimer	These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Reference Data
RefSeq	NM_001308360, NM_170776
Synonyms	GPR97; PB99; PGR26
Summary	Orphan receptor that regulates migration of lymphatic endothelial cells in vitro via the small GTPases RhoA and CDC42 (PubMed:24178298). Regulates B-cell development (By similarity). Seems to signal through G-alpha(q)-proteins (PubMed:22575658).[UniProtKB/Swiss-Prot Function]

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