Human PAOX activation kit by CRISPRa
CAT#: GA116286
PAOX CRISPRa kit - CRISPR gene activation of human polyamine oxidase
CNY 12,255.00
Specifications
Product Data | |
Format | 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug) |
Symbol | PAOX |
Locus ID | 196743 |
Kit Components | GA116286G1, PAOX gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA116286G2, PAOX gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA116286G3, PAOX gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077 |
Disclaimer | These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc. |
Reference Data | |
RefSeq | NM_152911, NM_207125, NM_207126, NM_207127, NM_207128, NM_207129, NR_109763, NR_109764, NR_109765, NR_109766 |
Synonyms | PAO |
Summary | Flavoenzyme which catalyzes the oxidation of N(1)-acetylspermine to spermidine and is thus involved in the polyamine back-conversion (PubMed:12477380). Can also oxidize N(1)-acetylspermidine to putrescine. Substrate specificity: N(1)-acetylspermine = N(1)-acetylspermidine > N(1),N(12)-diacylspermine >> spermine. Does not oxidize spermidine. Plays an important role in the regulation of polyamine intracellular concentration and has the potential to act as a determinant of cellular sensitivity to the antitumor polyamine analogs (PubMed:12477380).[UniProtKB/Swiss-Prot Function] |
Documents
Resources
基因表达相关资源 |
Other Versions
SKU | Description | Size | Price |
---|---|---|---|
KN407663 | PAOX - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. |
CNY 8,680.00 |