Human Consortin (CNST) activation kit by CRISPRa
CAT#: GA116101
CNST CRISPRa kit - CRISPR gene activation of human consortin, connexin sorting protein
CNY 12,255.00
Specifications
Product Data | |
Format | 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug) |
Symbol | CNST |
Locus ID | 163882 |
Kit Components | GA116101G1, Consortin gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA116101G2, Consortin gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA116101G3, Consortin gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077 |
Disclaimer | These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc. |
Reference Data | |
RefSeq | NM_001139459, NM_152609 |
Synonyms | C1orf71; PPP1R64 |
Summary | Targeting of numerous transmembrane proteins to the cell surface is thought to depend on their recognition by cargo receptors that interact with the adaptor machinery for anterograde traffic at the distal end of the Golgi complex. Consortin (CNST) is an integral membrane protein that acts as a binding partner of connexins, the building blocks of gap junctions, and acts as a trans-Golgi network (TGN) receptor involved in connexin targeting to the plasma membrane and recycling from the cell surface (del Castillo et al., 2010 [PubMed 19864490]).[supplied by OMIM, Jun 2010] |
Documents
Resources
基因表达相关资源 |
Other Versions
SKU | Description | Size | Price |
---|---|---|---|
KN420892 | CNST - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. |
CNY 8,680.00 |