Human TDRD5 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	TDRD5
Locus ID	163589
Kit Components	GA116091G1, TDRD5 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA116091G2, TDRD5 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA116091G3, TDRD5 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Disclaimer	These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Reference Data
RefSeq	NM_001199085, NM_001199089, NM_001199091, NM_001199092, NM_173533, NM_001349923
Synonyms	TUDOR3
Summary	Required during spermiogenesis to participate in the repression transposable elements and prevent their mobilization, which is essential for the germline integrity. Probably acts via the piRNA metabolic process, which mediates the repression of transposable elements during meiosis by forming complexes composed of piRNAs and Piwi proteins and govern the methylation and subsequent repression of transposons. Required for chromatoid body (CB) assembly (By similarity).[UniProtKB/Swiss-Prot Function]

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