Human C13orf31 (LACC1) activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	LACC1
Locus ID	144811
Kit Components	GA115509G1, C13orf31 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA115509G2, C13orf31 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA115509G3, C13orf31 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Disclaimer	These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Reference Data
RefSeq	NM_001128303, NM_153218, NM_001350638, NM_001350639, NM_001350640, NM_001350641, NM_001350642, NM_001350643, NM_001350644, NM_001350645, NM_001350646, NM_001350647, NM_001350648
Synonyms	C13orf31; FAMIN
Summary	This gene encodes an oxidoreductase that promotes fatty-acid oxidation, with concomitant inflammasome activation, mitochondrial and NADPH-oxidase-dependent reactive oxygen species production, and bactericidal activity of macrophages. The encoded protein forms a complex with fatty acid synthase on peroxisomes and is thought to be modulated by peroxisome proliferator-activated receptor signaling events. Naturally occurring mutations in this gene are associated with inflammatory bowel disease, Behcet's disease, leprosy, ulcerative colitis, early-onset Crohn's disease, and systemic juvenile idiopathic arthritis. [provided by RefSeq, Apr 2017]

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