Human Granuphilin (SYTL4) activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	SYTL4
Locus ID	94121
Kit Components	GA114333G1, Granuphilin gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA114333G2, Granuphilin gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA114333G3, Granuphilin gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Disclaimer	These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Reference Data
RefSeq	NM_001129896, NM_001174068, NM_080737, NM_001370161, NM_001370162, NM_001370164, NM_001370166, NM_001370168, NM_001370160, NM_001370163, NM_001370165, NM_001370167, NM_001370169
Synonyms	SLP4
Summary	This gene encodes a member of the synaptotagmin like protein family. Members of this family are characterized by an N-terminal Rab27 binding domain and C-terminal tandem C2 domains. The encoded protein binds specific small Rab GTPases and is involved in intracellular membrane trafficking. This protein binds Rab27 and may be involved in inhibiting dense core vesicle exocytosis. Alternate splicing results in multiple transcript variants that encode the same protein. [provided by RefSeq, Mar 2010]

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