Human TIFA activation kit by CRISPRa

CAT#: GA114228

TIFA CRISPRa kit - CRISPR gene activation of human TRAF interacting protein with forkhead associated domain



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CNY 12,255.00


货期*
4周

规格
    • 1 kit

Product images

经常一起买 (2)
TIFA Antibody - middle region
    • 100 ul

CNY 5,250.00


TIFA (Myc-DDK-tagged)-Human TRAF-interacting protein with forkhead-associated domain (TIFA)
    • 10 ug

CNY 2,400.00
CNY 3,705.00

Specifications

Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol TIFA
Locus ID 92610
Kit Components

GA114228G1, TIFA gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA114228G2, TIFA gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA114228G3, TIFA gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077

Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Reference Data
RefSeq NM_052864
Synonyms T2BP; T6BP; TIFAA
Summary This gene encodes an adapter protein involved in adaptive and innate immunity. This protein includes a forkhead-associated (FHA) domain that specifically binds to phosphorylated serine and threonine residues. In response to bacterial infection, the encoded host cell protein undergoes an intermolecular interaction between the FHA domain and a phosphorylated threonine that leads to protein oligomerization and stimulation of the NF-kappa B and other downstream signaling pathways. This protein exhibits reduced expression in hepatocellular carcinoma and may suppress hepatocellular carcinoma progression. This protein may also play a role in the DNA damage response. [provided by RefSeq, Jun 2018]
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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