Human LYRIC (MTDH) activation kit by CRISPRa
CAT#: GA114185
MTDH CRISPRa kit - CRISPR gene activation of human metadherin
CNY 12,255.00
CNY 800.00
CNY 1,999.00
CNY 2,700.00
Specifications
Product Data | |
Format | 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug) |
Symbol | MTDH |
Locus ID | 92140 |
Kit Components | GA114185G1, LYRIC gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA114185G2, LYRIC gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA114185G3, LYRIC gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077 |
Disclaimer | These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc. |
Reference Data | |
RefSeq | NM_178812, NM_001363139, NM_001363136, NM_001363137, NM_001363138 |
Synonyms | 3D3; AEG-1; AEG1; LYRIC; LYRIC/3D3 |
Summary | Downregulates SLC1A2/EAAT2 promoter activity when expressed ectopically. Activates the nuclear factor kappa-B (NF-kappa-B) transcription factor. Promotes anchorage-independent growth of immortalized melanocytes and astrocytes which is a key component in tumor cell expansion. Promotes lung metastasis and also has an effect on bone and brain metastasis, possibly by enhancing the seeding of tumor cells to the target organ endothelium. Induces chemoresistance.[UniProtKB/Swiss-Prot Function] |
Documents
Resources
基因表达相关资源 |
Other Versions
SKU | Description | Size | Price |
---|---|---|---|
KN407238 | MTDH - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. |
CNY 8,680.00 |