Human FAM105B (OTULIN) activation kit by CRISPRa
CAT#: GA113994
OTULIN CRISPRa kit - CRISPR gene activation of human OTU deubiquitinase with linear linkage specificity
CNY 12,255.00
Specifications
Product Data | |
Format | 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug) |
Symbol | OTULIN |
Locus ID | 90268 |
Kit Components | GA113994G1, FAM105B gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA113994G2, FAM105B gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA113994G3, FAM105B gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077 |
Disclaimer | These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc. |
Reference Data | |
RefSeq | NM_138348 |
Synonyms | AIPDS; FAM105B; GUM |
Summary | This gene encodes a member of the peptidase C65 family of ubiquitin isopeptidases. Members of this family remove ubiquitin from proteins. The encoded enzyme specifically recognizes and removes M1(Met1)-linked, or linear, ubiquitin chains from protein substrates. Linear ubiquitin chains are known to regulate the NF-kappa B signaling pathway in the context of immunity and inflammation. Mutations in this gene cause a potentially fatal autoinflammatory syndrome in human patients. [provided by RefSeq, Sep 2016] |
Documents
Resources
基因表达相关资源 |
Other Versions
SKU | Description | Size | Price |
---|---|---|---|
KN424840 | OTULIN - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. |
CNY 8,680.00 |