Human HSH2D activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	HSH2D
Locus ID	84941
Kit Components	GA113786G1, HSH2D gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA113786G2, HSH2D gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA113786G3, HSH2D gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Disclaimer	These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Reference Data
RefSeq	NM_001291274, NM_032855, NR_111903, NR_111904, NM_001352265, NM_001352266, NM_001369808, NR_163150, NR_163152, NR_163153, NR_163155, NM_001369809, NR_163151, NR_163154, NR_163156
Synonyms	ALX; HSH2
Summary	T-cell activation requires 2 signals: recognition of antigen by the T-cell receptor (see TCR; MIM 186880) and a costimulatory signal provided primarily by CD28 (MIM 186760) in naive T cells. HSH2 is a target of both of these signaling pathways (Greene et al., 2003 [PubMed 12960172]).[supplied by OMIM, Mar 2008]

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