Human ATAD1 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	ATAD1
Locus ID	84896
Kit Components	GA113748G1, ATAD1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA113748G2, ATAD1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA113748G3, ATAD1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Disclaimer	These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Reference Data
RefSeq	NM_001321967, NM_001321968, NM_001321969, NM_032810, NR_135914
Synonyms	AFDC1; FNP001; THORASE
Summary	ATPase that plays a critical role in regulating the surface expression of AMPA receptors (AMPAR), thereby regulating synaptic plasticity and learning and memory. Required for NMDA-stimulated AMPAR internalization and inhibition of GRIA1 and GRIA2 recycling back to the plasma membrane; these activities are ATPase-dependent (By similarity).[UniProtKB/Swiss-Prot Function]

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