Human MLK4 (MAP3K21) activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	MAP3K21
Locus ID	84451
Kit Components	GA113556G1, MLK4 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA113556G2, MLK4 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA113556G3, MLK4 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Disclaimer	These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Reference Data
RefSeq	NM_032435
Synonyms	dJ862P8.3; MLK4
Summary	Negative regulator of TLR4 signaling. Does not activate JNK1/MAPK8 pathway, p38/MAPK14, nor ERK2/MAPK1 pathways.[UniProtKB/Swiss-Prot Function]

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