Human CARD11 activation kit by CRISPRa

CAT#: GA113541

CARD11 CRISPRa kit - CRISPR gene activation of human caspase recruitment domain family member 11



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CNY 12,255.00


货期*
4周

规格
    • 1 kit

Product images

经常一起买 (3)
Rabbit Polyclonal Anti-CARD11 Antibody
    • 100 ul

CNY 1,999.00
CNY 3,280.00


CARD11 (Myc-DDK-tagged)-Human caspase recruitment domain family, member 11 (CARD11)
    • 10 ug

CNY 12,048.00


CARD11 Rabbit polyclonal Antibody
    • 100 ul

CNY 1,999.00
CNY 3,280.00

Specifications

Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol CARD11
Locus ID 84433
Kit Components

GA113541G1, CARD11 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA113541G2, CARD11 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA113541G3, CARD11 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077

Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Reference Data
RefSeq NM_001324281, NM_032415
Synonyms BENTA; BIMP3; CARMA1; IMD11; PPBL
Summary The protein encoded by this gene belongs to the membrane-associated guanylate kinase (MAGUK) family, a class of proteins that functions as molecular scaffolds for the assembly of multiprotein complexes at specialized regions of the plasma membrane. This protein is also a member of the CARD protein family, which is defined by carrying a characteristic caspase-associated recruitment domain (CARD). This protein has a domain structure similar to that of CARD14 protein. The CARD domains of both proteins have been shown to specifically interact with BCL10, a protein known to function as a positive regulator of cell apoptosis and NF-kappaB activation. When expressed in cells, this protein activated NF-kappaB and induced the phosphorylation of BCL10. [provided by RefSeq, Jul 2008]
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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