Human COA8 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	COA8
Locus ID	84334
Kit Components	GA113526G1, COA8 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA113526G2, COA8 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA113526G3, COA8 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Disclaimer	These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Reference Data
RefSeq	NM_001302652, NM_001302653, NM_001302654, NM_032374, NR_126431, NR_126432, NM_001370595
Synonyms	APOP; APOP1; C14orf153
Summary	This gene encodes a protein that localizes to the mitochondria, where it stimulates the release of cytochrome c, thereby promoting programmed cell death. Mutations in this gene have been found in individuals with mitochondrial complex IV deficiency. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Nov 2014]

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