Human RPAIN activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	RPAIN
Locus ID	84268
Kit Components	GA113465G1, RPAIN gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA113465G2, RPAIN gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA113465G3, RPAIN gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Disclaimer	These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Reference Data
RefSeq	NM_001033002, NM_001160243, NM_001160244, NM_001160246, NM_001160266, NM_001160267, NM_032308, NR_027678, NR_027679, NR_027680, NR_027681, NR_027682, NR_027683, NR_027684, NR_027685, N41653
Synonyms	HRIP; RIP
Summary	Mediates the import of RPA complex into the nucleus, possibly via some interaction with importin beta. Isoform 2 is sumoylated and mediates the localization of RPA complex into the PML body of the nucleus, thereby participating in RPA function in DNA metabolism.[UniProtKB/Swiss-Prot Function]

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