Human SETDB2 activation kit by CRISPRa

CAT#: GA113273

SETDB2 CRISPRa kit - CRISPR gene activation of human SET domain bifurcated histone lysine methyltransferase 2



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CNY 12,255.00


货期*
4周

规格
    • 1 kit

Product images

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Specifications

Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol SETDB2
Locus ID 83852
Kit Components

GA113273G1, SETDB2 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA113273G2, SETDB2 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA113273G3, SETDB2 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077

Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Reference Data
RefSeq NM_001160308, NM_031915, NM_001320699
Synonyms C13orf4; CLLD8; CLLL8; KMT1F
Summary This gene encodes a member of a family of proteins that contain a methyl-CpG-binding domain (MBD) and a SET domain and function as histone methyltransferases. This protein is recruited to heterochromatin and plays a role in the regulation of chromosome segregation. This region is commonly deleted in chronic lymphocytic leukemia. Naturally-occuring readthrough transcription occurs from this gene to the downstream PHF11 (PHD finger protein 11) gene. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Mar 2016]
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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