Human LMAN2L activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	LMAN2L
Locus ID	81562
Kit Components	GA113067G1, LMAN2L gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA113067G2, LMAN2L gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA113067G3, LMAN2L gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Disclaimer	These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Reference Data
RefSeq	NM_001142292, NM_001322346, NM_001322347, NM_001322350, NM_001322351, NM_001322352, NM_001322354, NM_001322355, NM_001322356, NM_030805, NR_024518, NR_024519, NR_024520, NR_024521
Synonyms	MRT52; VIPL
Summary	This gene encodes a protein belonging to the L-type lectin group of type 1 membrane proteins, which function in the mammalian early secretory pathway. These proteins contain luminal carbohydrate recognition domains, which display homology to leguminous lectins. Unlike other proteins of the group, which cycle in the early secretory pathway and are predominantly associated with post endoplasmic reticulum membranes, the protein encoded by this gene is a non-cycling resident protein of the ER, where it functions as a cargo receptor for glycoproteins. It is proposed to regulate exchange of folded proteins for transport to the Golgi and exchange of misfolded glycoproteins for transport to the ubiquitin-proteasome pathway. [provided by RefSeq, Apr 2016]

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