Human COLEC12 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	COLEC12
Locus ID	81035
Kit Components	GA113017G1, COLEC12 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA113017G2, COLEC12 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA113017G3, COLEC12 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Disclaimer	These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Reference Data
RefSeq	NM_030781, NM_130386
Synonyms	CLP1; CLP1, NSR2, SRCL, SCARA4; collectin placenta 1; collectin sub-family member 12; NSR2; nurse cell scavenger receptor 2; SCARA4; scavenger receptor class A, member 4; scavenger receptor with C-type lectin; SRCL
Summary	This gene encodes a member of the C-lectin family, proteins that possess collagen-like sequences and carbohydrate recognition domains. This protein is a scavenger receptor that displays several functions associated with host defense. It can bind to carbohydrate antigens on microorganisms, facilitating their recognition and removal. It also mediates the recognition, internalization, and degradation of oxidatively modified low density lipoprotein by vascular endothelial cells. [provided by RefSeq, May 2018]

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