Human PAQR6 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	PAQR6
Locus ID	79957
Kit Components	GA112755G1, PAQR6 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA112755G2, PAQR6 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA112755G3, PAQR6 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Disclaimer	These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Reference Data
RefSeq	NM_001272104, NM_001272105, NM_001272106, NM_001272107, NM_001272108, NM_001272109, NM_001272110, NM_001272111, NM_001272112, NM_001272113, NM_024897, NM_198406, NR_073610
Synonyms	PRdelta
Summary	Plasma membrane progesterone (P4) receptor coupled to G proteins (PubMed:23763432, PubMed:23161870). Seems to act through a G(s) mediated pathway (PubMed:23161870). Involved in neurosteroid inhibition of apoptosis (PubMed:23161870). May be involved in regulating rapid P4 signaling in the nervous system (PubMed:23763432). Also binds dehydroepiandrosterone (DHEA), pregnanolone, pregnenolone and allopregnanolone (PubMed:23763432, PubMed:23161870).[UniProtKB/Swiss-Prot Function]

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