Human NEK11 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	NEK11
Locus ID	79858
Kit Components	GA112682G1, NEK11 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA112682G2, NEK11 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA112682G3, NEK11 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Disclaimer	These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Reference Data
RefSeq	NM_001146003, NM_001321220, NM_001321221, NM_001321222, NM_001321223, NM_001321224, NM_024800, NM_145910, NM_001353022, NM_001353023, NM_001353024, NM_001353025, NM_001353026, NM_001353027, NM_001353028, NM_001353029, NM_001353030, NM_001353031, NM_001353032, NM_001353033, NM_001353034, NM_001353036, NM_001353037, NM_001353038, NM_001353039, NM_001353040, NM_001353041, NM_001353042, NM_001353043, NM_001353044, NM_001353045, NM_001353046, NM_001353048
Synonyms	FLJ23495
Summary	This gene encodes a member of the never in mitosis gene A family of kinases. The encoded protein localizes to the nucleoli, and may function with NEK2A in the S-phase checkpoint. The encoded protein appears to play roles in DNA replication and response to genotoxic stress. Alternatively spliced transcript variants have been described.[provided by RefSeq, Mar 2009]

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