Human Gasdermin D (GSDMD) activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	GSDMD
Locus ID	79792
Kit Components	GA112629G1, Gasdermin D gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA112629G2, Gasdermin D gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA112629G3, Gasdermin D gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Disclaimer	These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Reference Data
RefSeq	NM_001166237, NM_024736
Synonyms	DF5L; DFNA5L; FKSG10; GSDMDC1
Summary	Gasdermin D is a member of the gasdermin family. Members of this family appear to play a role in regulation of epithelial proliferation. Gasdermin D has been suggested to act as a tumor suppressor. Alternatively spliced transcript variants have been described. [provided by RefSeq, Oct 2009]

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