Human RHBDF2 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	RHBDF2
Locus ID	79651
Kit Components	GA112520G1, RHBDF2 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA112520G2, RHBDF2 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA112520G3, RHBDF2 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Disclaimer	These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Reference Data
RefSeq	NM_001005498, NM_024599
Synonyms	iRhom2; RHBDL5; RHBDL6; TEC; TOC; TOCG
Summary	Regulates ADAM17 protease, a sheddase of the epidermal growth factor (EGF) receptor ligands and TNF, thereby plays a role in sleep, cell survival, proliferation, migration and inflammation. Does not exhibit any protease activity on its own.[UniProtKB/Swiss-Prot Function]

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