Human BRIT1 (MCPH1) activation kit by CRISPRa

CAT#: GA112517

MCPH1 CRISPRa kit - CRISPR gene activation of human microcephalin 1



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CNY 12,255.00


货期*
4周

规格
    • 1 kit

Product images

经常一起买 (3)
MCPH1 mouse monoclonal antibody, clone OTI2A3 (formerly 2A3)
    • 100 ul

CNY 1,999.00
CNY 2,700.00


MCPH1 (Myc-DDK-tagged)-Human microcephalin 1 (MCPH1), transcript variant 1
    • 10 ug

CNY 6,120.00
CNY 7,130.00


MCPH1 mouse monoclonal antibody, clone OTI3H9 (formerly 3H9)
    • 30 ul

CNY 800.00

Specifications

Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol MCPH1
Locus ID 79648
Kit Components

GA112517G1, BRIT1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA112517G2, BRIT1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA112517G3, BRIT1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077

Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Reference Data
RefSeq NM_001172574, NM_001172575, NM_001322042, NM_001322043, NM_001322045, NM_024596, NR_136159, NM_001363979, NM_001363980
Synonyms BRIT1; MCT
Summary This gene encodes a DNA damage response protein. The encoded protein may play a role in G2/M checkpoint arrest via maintenance of inhibitory phosphorylation of cyclin-dependent kinase 1. Mutations in this gene have been associated with primary autosomal recessive microcephaly 1 and premature chromosome condensation syndrome. Alternatively spliced transcript variants have been described. [provided by RefSeq, Feb 2010]
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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