Human KREMEN2 activation kit by CRISPRa

CAT#: GA112439

KREMEN2 CRISPRa kit - CRISPR gene activation of human kringle containing transmembrane protein 2



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CNY 12,255.00


货期*
4周

规格
    • 1 kit

Product images

经常一起买 (3)
Rabbit Polyclonal KREMEN2 Antibody
    • 100 ug

CNY 5,808.00


KREMEN2 (Myc-DDK-tagged)-Human kringle containing transmembrane protein 2 (KREMEN2), transcript variant 2
    • 10 ug

CNY 3,656.00
CNY 3,990.00


KREMEN2 Rabbit polyclonal Antibody
    • 100 ul

CNY 1,999.00
CNY 3,280.00

Specifications

Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol KREMEN2
Locus ID 79412
Kit Components

GA112439G1, KREMEN2 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA112439G2, KREMEN2 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA112439G3, KREMEN2 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077

Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Reference Data
RefSeq NM_001253725, NM_001253726, NM_024507, NM_145347, NM_145348, NM_172229
Synonyms KRM2
Summary This gene encodes a high-affinity dickkopf homolog 1 (DKK1) transmembrane receptor. A similar protein in mouse functions interacts with with DKK1 to block wingless (WNT)/beta-catenin signaling. The encoded protein forms a ternary membrane complex with DKK1 and the WNT receptor lipoprotein receptor-related protein 6 (LRP6), and induces rapid endocytosis and removal of LRP6 from the plasma membrane. It contains extracellular kringle, WSC, and CUB domains. Alternatively spliced transcript variants encoding distinct isoforms have been observed for this gene. [provided by RefSeq, Dec 2011]
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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