Human C19orf50 (KXD1) activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	KXD1
Locus ID	79036
Kit Components	GA112327G1, C19orf50 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA112327G2, C19orf50 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA112327G3, C19orf50 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Disclaimer	These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Reference Data
RefSeq	NM_001171948, NM_001171949, NM_024069
Synonyms	C19orf50; KXDL; MST096; MSTP096
Summary	As part of the BORC complex may play a role in lysosomes movement and localization at the cell periphery. Associated with the cytosolic face of lysosomes, the BORC complex may recruit ARL8B and couple lysosomes to microtubule plus-end-directed kinesin motor (PubMed:25898167). May be involved in the biogenesis of lysosome-related organelles such as melanosomes (By similarity).[UniProtKB/Swiss-Prot Function]

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